Dual control of subtilin biosynthesis and immunity in Bacillus subtilis

نویسندگان
چکیده

منابع مشابه

Autoregulation of subtilin biosynthesis in Bacillus subtilis: the role of the spa-box in subtilin-responsive promoters.

The production of the type I antimicrobial peptide (AMP) subtilin by Bacillus subtilis is regulated in a cell-density-dependent manner [Kleerebezem M, de Vos WM, Kuipers OP. The lantibiotics nisin and subtilin act as extracellular regulators of their own biosynthesis. In: Dunny GM, Winans SC, editors. Cell-cell signaling in bacteria. Washington, D.C., USA: ASM Press; 1999. p. 159-74; Stein T, B...

متن کامل

Modeling Subtilin Production in Bacillus subtilis Using Stochastic Hybrid Systems

The genetic network regulating the biosynthesis of subtilin in Bacillus subtilis is modeled as a stochastic hybrid system. The continuous state of the hybrid system is the concentrations of subtilin and various regulating proteins, whose productions are controlled by switches in the genetic network that are in turn modeled as Markov chains. Some preliminary results are given by both analysis an...

متن کامل

Dual substrate specificity of Bacillus subtilis PBP4a.

Bacterial dd-peptidases are the targets of the β-lactam antibiotics. The sharp increase in bacterial resistance toward these antibiotics in recent years has stimulated the search for non-β-lactam alternatives. The substrates of dd-peptidases are elements of peptidoglycan from bacterial cell walls. Attempts to base dd-peptidase inhibitor design on peptidoglycan structure, however, have not been ...

متن کامل

Effect of Bacillus subtilis IS02 in food on health, immunity indexes and prevention against White Spot Disease in Litopenaeus vannamei

    In this study, “Tak Cell” probiotic, based on eight-year studies (2009- 2016) of the Iranian Fisheries Sciences Research Institute in National Shrimp Research Institute, and produced in collaboration with the “Tak Zhen Zist ®” company, was added to the diet of western white shrimp (Litopenaeus vannamei) weighing more than 6 grams (in three Different quantities 106, 107 and 108 CFU/Kg) and h...

متن کامل

Subtilin Production by Bacillus Subtilis: Stochastic Hybrid Models and Parameter Identification

This paper presents methods for the parameter identification of a model of subtilin production by Bacillus subtilis. Based on a stochastic hybrid model, identification is split in two subproblems: estimation of the genetic network regulating subtilin production from gene expression data, and estimation of population dynamics based on nutrient and population level data. Techniques for identifica...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Molecular Microbiology

سال: 2002

ISSN: 0950-382X,1365-2958

DOI: 10.1046/j.1365-2958.2002.02869.x